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Esophageal cancer is the sixth most common cause of cancer-related mortality worldwide because of its poor prognosis (1). Advanced esophageal cancer cannot be cured by a traditional monotherapy method; instead a multidisciplinary therapy is required. Many therapeutic strategies have been developed to date, and several controlled studies have been performed to ensure their efficacy.

The significance of surgery following concurrent chemoradiotherapy for locally advanced esophageal squamous cell carcinoma