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Neutrophil gelatinase-associated lipocalin as a complementary biomarker for the asthma-chronic obstructive pulmonary disease overlap
Author(s) -
Yong Suk Jo,
Sung Ok Kwon,
Jee-Young Kim,
Woo Jin Kim
Publication year - 2018
Publication title -
journal of thoracic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 60
eISSN - 2077-6624
pISSN - 2072-1439
DOI - 10.21037/jtd.2018.07.86
Subject(s) - medicine , asthma , biomarker , lipocalin , pulmonary disease , disease , neutrophil gelatinase associated lipocalin , gelatinase , intensive care medicine , immunology , matrix metalloproteinase , biochemistry , chemistry
There is no standardized definition of the asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO). Although the blood eosinophil count is regarded as a biomarker for identifying ACO, it has no distinct value. This study aimed to measure plasma levels of neutrophil gelatinase-associated lipocalin (NGAL), a potential biomarker for distinguishing between ACO and non-ACO COPD.

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