Combining immunotherapy with radiation therapy in thoracic oncology
Author(s) -
Shahed N. Badiyan,
Michael Roach,
Michael D. Chuong,
Stephanie R. Rice,
N. Onyeuku,
Jill Remick,
Srinivas Chilukuri,
Erica Glass,
Pranshu Mohindra,
Charles B. Simone
Publication year - 2018
Publication title -
journal of thoracic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 60
eISSN - 2077-6624
pISSN - 2072-1439
DOI - 10.21037/jtd.2018.05.73
Subject(s) - medicine , immunotherapy , radiation therapy , oncology , clinical trial , lung cancer , radiation oncology , targeted therapy , cancer
Thoracic malignancies comprise some of the most common and deadly cancers. Immunotherapies have been proven to improve survival outcomes for patients with advanced non-small cell lung cancer (NSCLC) and show great potential for patients with other thoracic malignancies. Radiation therapy (RT), an established and effective treatment for thoracic cancers, has acted synergistically with immunotherapies in preclinical studies. Ongoing clinical trials are exploring the clinical benefits of combining RT with immunotherapies and the optimal manner in which to deliver these complementary treatments.
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