Suppression of mitochondrial respiration with local anesthetic ropivacaine targets breast cancer cells
Author(s) -
Xiaodan Gong,
Jiapeng Dan,
Fang Li,
Lishen Wang
Publication year - 2018
Publication title -
journal of thoracic disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.682
H-Index - 60
eISSN - 2077-6624
pISSN - 2072-1439
DOI - 10.21037/jtd.2018.05.21
Subject(s) - ropivacaine , medicine , respiration , breast cancer , anesthetic , anesthesia , cancer , bioinformatics , pharmacology , oncology , biology , anatomy
Retrospective studies on cancer patients who have received local anesthesia show a favorable decrease in tumor metastasis and recurrence. However, the mechanisms underlying the benefits of local anesthesia on cancer recurrence are not well understood.
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