Next-generation sequencing for identifying genetic mutations in adults with bronchiectasis | Zendy

Weijie Guan | Zendy; Jia-Cheng Li | Zendy; Fang Liu | Zendy; Jian Zhou | Zendy; Yaping Liu | Zendy; Chao Ling | Zendy; Yonghua Gao | Zendy; Huimin Li | Zendy; Jing-Jing Yuan | Zendy; Yan Huang | Zendy; Chunlan Chen | Zendy; Rongchang Chen | Zendy; Xue Zhang | Zendy; Nanshan Zhong | Zendy

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Next-generation sequencing for identifying genetic mutations in adults with bronchiectasis

Author(s) -

Weijie Guan,

Jia-Cheng Li,

Fang Liu,

Jian Zhou,

Yaping Liu,

Chao Ling,

Yonghua Gao,

Huimin Li,

Jing-Jing Yuan,

Yan Huang,

Chunlan Chen,

Rongchang Chen,

Xue Zhang,

Nanshan Zhong

Publication year - 2018

Publication title -

journal of thoracic disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.682

H-Index - 60

eISSN - 2077-6624

pISSN - 2072-1439

DOI - 10.21037/jtd.2018.04.134

Subject(s) - bronchiectasis , primary ciliary dyskinesia , pathogenesis , medicine , cystic fibrosis , immunology , genetics , pathology , lung , biology

Defective airway host-defense (e.g., altered mucus properties, ciliary defects) contributes to the pathogenesis of bronchiectasis. This study aims to determine whether genetic mutations associated with defective airway host-defense are implicated in the pathogenesis of bronchiectasis.

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