Impact of radiotherapy duration on overall survival in squamous cell carcinoma of the anus | Zendy

Shahil Mehta | Zendy; Stephen J. Ramey | Zendy; Deukwoo Kwon | Zendy; Benjamin Rich | Zendy; Awad A. Ahmed | Zendy; Aaron H. Wolfson | Zendy; Raphael Yechieli | Zendy; Lorraine Portelance | Zendy; Eric A. Mellon | Zendy

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Impact of radiotherapy duration on overall survival in squamous cell carcinoma of the anus

Author(s) -

Shahil Mehta,

Stephen J. Ramey,

Deukwoo Kwon,

Benjamin Rich,

Awad A. Ahmed,

Aaron H. Wolfson,

Raphael Yechieli,

Lorraine Portelance,

Eric A. Mellon

Publication year - 2020

Publication title -

journal of gastrointestinal oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.084

H-Index - 39

eISSN - 2219-679X

pISSN - 2078-6891

DOI - 10.21037/jgo.2020.02.09

Subject(s) - medicine , proportional hazards model , radiation therapy , anal cancer , survival analysis , anus , hazard ratio , cancer , oncology , basal cell , surgery , urology , confidence interval

Prolongation of radiotherapy (RT) in the treatment of numerous types of cancer has been shown to reduce overall survival (OS). Treatment delays are common in squamous cell carcinoma of the anus (SCCA) due to the toxicity of definitive chemoradiation (CRT). The effect of these delays on outcomes has not been well evaluated. This study investigated the effects of RT prolongation on OS in patients receiving CRT for SCCA.

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