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Safety and efficacy of locoregional therapy for metastatic pancreatic ductal adenocarcinoma to the liver: a single-center experience
Author(s) -
Ryan E. Bailey,
Phani Keerthi Surapaneni,
Jacob Core,
Lucas Lauar Cortizo Vidal,
Jordan D. LeGout,
Charles Ritchie,
G. Frey,
J. Mark McKinney,
David M. Sella,
Ricardo PazFumagalli,
Beau Toskich,
Kabir Mody
Publication year - 2019
Publication title -
journal of gastrointestinal oncology
Language(s) - English
Resource type - Journals
eISSN - 2219-679X
pISSN - 2078-6891
DOI - 10.21037/jgo.2019.03.13
Subject(s) - medicine , response evaluation criteria in solid tumors , adverse effect , single center , progressive disease , stage (stratigraphy) , chemotherapy , pancreatic ductal adenocarcinoma , oncology , pancreatic cancer , surgery , radiology , gastroenterology , cancer , paleontology , biology
Many patients with pancreatic ductal adenocarcinoma (PDAC) are diagnosed with liver metastatic disease (mPDAC), and few are surgical candidates. Interventional oncology (IO) locoregional therapies (LRT) have proven beneficial in other primary and metastatic hepatic malignancies. Systemic chemotherapy is the standard of care for patients with mPDAC. This study assessed the safety and efficacy of LRT including thermal ablation, chemoembolization, and radioembolization for mPDAC.

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