Comparison of tumor regression grading system in locally advanced esophageal squamous cell carcinoma after preoperative radio-chemotherapy to determine the most accurate system predicting prognosis | Zendy

Nathawadee Lerttanatum | Zendy; Chadin Tharavej | Zendy; Yuda Chongpison | Zendy; Anapat Sanpavat | Zendy

Open Access

Comparison of tumor regression grading system in locally advanced esophageal squamous cell carcinoma after preoperative radio-chemotherapy to determine the most accurate system predicting prognosis

Author(s) -

Nathawadee Lerttanatum,

Chadin Tharavej,

Yuda Chongpison,

Anapat Sanpavat

Publication year - 2019

Publication title -

journal of gastrointestinal oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.084

H-Index - 39

eISSN - 2219-679X

pISSN - 2078-6891

DOI - 10.21037/jgo.2018.12.01

Subject(s) - medicine , proportional hazards model , esophageal cancer , survival analysis , akaike information criterion , grading (engineering) , hazard ratio , oncology , carcinoma , esophagectomy , log rank test , lymph node , cancer , statistics , nuclear medicine , mathematics , confidence interval , civil engineering , engineering

Nowadays, preoperative radio-chemotherapy is a standard treatment for locally advanced esophageal squamous cell carcinoma (ESCC). Tumor regression grade (TRG), referring to a classification of cancer response to preoperative treatment, can predict a prognosis of survival. Many TRG systems are proposed for use in esophageal cancer, but none of them has become standard grading system. This research compared five TRG systems, including Mandard system, Chirieac system, Schneider system, Hermann system, and Japan Esophageal Society (JES) system, to find the most accurately predictive system.

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