Molecular profiling of biliary cancers reveals distinct molecular alterations and potential therapeutic targets | Zendy

Benjamin A. Weinberg | Zendy; Joanne Xiu | Zendy; Michael Lindberg | Zendy; Anthony F. Shields | Zendy; Jimmy J. Hwang | Zendy; Kelsey Poorman | Zendy; Mohamed E. Salem | Zendy; Michael J. Pishvaian | Zendy; Randall F. Holcombe | Zendy; John Marshall | Zendy; Michael A. Morse | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Molecular profiling of biliary cancers reveals distinct molecular alterations and potential therapeutic targets

Author(s) -

Benjamin A. Weinberg,

Joanne Xiu,

Michael Lindberg,

Anthony F. Shields,

Jimmy J. Hwang,

Kelsey Poorman,

Mohamed E. Salem,

Michael J. Pishvaian,

Randall F. Holcombe,

John Marshall,

Michael A. Morse

Publication year - 2019

Publication title -

journal of gastrointestinal oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.084

H-Index - 39

eISSN - 2219-679X

pISSN - 2078-6891

DOI - 10.21037/jgo.2018.08.18

Subject(s) - microsatellite instability , cdkn2a , kras , medicine , cancer research , idh1 , targeted therapy , intrahepatic cholangiocarcinoma , oncology , cancer , biology , mutation , gene , genetics , microsatellite , colorectal cancer , allele

Biliary tract cancers (BTCs) are a heterogeneous group of aggressive, rare malignancies with limited standard chemotherapeutic options for advanced disease. Recent studies have demonstrated potential novel biliary cancer targets and a possible role for immunotherapy in the treatment of patients with this disease. Intrahepatic cholangiocarcinoma (IHCC), extrahepatic cholangiocarcinoma (EHCC), and gallbladder carcinoma (GBC) are frequently grouped together in clinical trials despite differences in tumor biology.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research