Impact of sarcopenia in borderline resectable and locally advanced pancreatic cancer patients receiving stereotactic body radiation therapy | Zendy

William Jin | Zendy; Eric A. Mellon | Zendy; Jessica M. Frakes | Zendy; Gilbert Z. Murimwa | Zendy; Pamela J. Hodul | Zendy; José M. Pimiento | Zendy; Mokenge P. Malafa | Zendy; Sarah E. Hoffe | Zendy

Open Access

Impact of sarcopenia in borderline resectable and locally advanced pancreatic cancer patients receiving stereotactic body radiation therapy

Author(s) -

William Jin,

Eric A. Mellon,

Jessica M. Frakes,

Gilbert Z. Murimwa,

Pamela J. Hodul,

José M. Pimiento,

Mokenge P. Malafa,

Sarah E. Hoffe

Publication year - 2018

Publication title -

journal of gastrointestinal oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.084

H-Index - 39

eISSN - 2219-679X

pISSN - 2078-6891

DOI - 10.21037/jgo.2017.09.13

Subject(s) - medicine , sarcopenia , pancreatic cancer , nausea , chemoradiotherapy , radiology , body mass index , cancer , oncology , nuclear medicine

Total psoas area (TPA), a marker of sarcopenia, has been used as an independent predictor of clinical outcomes in gastrointestinal (GI) cancers as a proxy for frailty and nutritional status. Our study aimed to evaluate whether TPA, in contrast to traditional measurements of nutrition like body mass index (BMI) and body surface area (BSA), was predictive of outcomes in borderline resectable pancreatic cancer (BRPC) and locally advanced pancreatic cancer (LAPC) patients receiving stereotactic body radiation therapy (SBRT).

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