Development and verification of a hypoxia- and immune-associated prognosis signature for esophageal squamous cell carcinoma | Zendy

Lian Lian | Zendy; Shibing Teng | Zendy; Youyou Xia | Zendy; Xiaoming Shen | Zendy; Yan Zheng | Zendy; Shu-Guang Han | Zendy; Wenjie Wang | Zendy; Xuefei Xu | Zendy; Chong Zhou | Zendy

Open Access

Development and verification of a hypoxia- and immune-associated prognosis signature for esophageal squamous cell carcinoma

Author(s) -

Lian Lian,

Shibing Teng,

Youyou Xia,

Xiaoming Shen,

Yan Zheng,

Shu-Guang Han,

Wenjie Wang,

Xuefei Xu,

Chong Zhou

Publication year - 2022

Publication title -

journal of gastrointestinal oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.084

H-Index - 39

eISSN - 2219-679X

pISSN - 2078-6891

DOI - 10.21037/jgo-22-69

Subject(s) - nomogram , proportional hazards model , univariate analysis , medicine , oncology , immune system , esophageal squamous cell carcinoma , survival analysis , gene , cancer research , carcinoma , multivariate analysis , biology , immunology , genetics

Esophageal cancer is one of the most common gastrointestinal malignancies worldwide, with high morbidity and mortality in China. The clinical importance of the interaction between hypoxia and immune status in the tumor microenvironment has been established in esophageal squamous cell carcinoma (ESCC). This study aims to develop a new hypoxia- and immune-based gene signature to predict the survival of ESCC patients.

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