High expression of aldolase A is associated with tumor progression and poor prognosis in hepatocellular carcinoma | Zendy

Yan Tang | Zendy; Xuefeng Yang | Zendy; Kehai Feng | Zendy; Chang-Lu Hu | Zendy; Suyi Li | Zendy

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High expression of aldolase A is associated with tumor progression and poor prognosis in hepatocellular carcinoma

Author(s) -

Yan Tang,

Xuefeng Yang,

Kehai Feng,

Chang-Lu Hu,

Suyi Li

Publication year - 2021

Publication title -

journal of gastrointestinal oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.084

H-Index - 39

eISSN - 2219-679X

pISSN - 2078-6891

DOI - 10.21037/jgo-20-534

Subject(s) - cancer research , aldolase a , hepatocellular carcinoma , biology , proportional hazards model , glycolysis , oncology , medicine , enzyme , biochemistry , metabolism

Aldolase A (ALDOA), a key glycolytic enzyme, has been reported to play an important role in lung, pancreatic, and colorectal cancer. However, the role and mechanism of ALDOA in hepatocellular carcinoma (HCC) are still unclear. This study aimed to study the role and potential mechanism of ALDOA in HCC.

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