Novel lymphocyte to red blood cell ratio (LRR), neutrophil to red blood cell ratio (NRR), monocyte to red blood cell ratio (MRR) as predictive and prognostic biomarkers for locally advanced breast cancer | Zendy

Yaohui Wang | Zendy; Haofeng Wang | Zendy; Wenjin Yin | Zendy; Yanping Lin | Zendy; Liheng Zhou | Zendy; Xiaonan Sheng | Zendy; Yaqian Xu | Zendy; Rui Sha | Zendy; Jinsong Lu | Zendy

Open Access

Novel lymphocyte to red blood cell ratio (LRR), neutrophil to red blood cell ratio (NRR), monocyte to red blood cell ratio (MRR) as predictive and prognostic biomarkers for locally advanced breast cancer

Author(s) -

Yaohui Wang,

Haofeng Wang,

Wenjin Yin,

Yanping Lin,

Liheng Zhou,

Xiaonan Sheng,

Yaqian Xu,

Rui Sha,

Jinsong Lu

Publication year - 2019

Publication title -

gland surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.643

H-Index - 22

eISSN - 2227-8575

pISSN - 2227-684X

DOI - 10.21037/gs.2019.10.10

Subject(s) - medicine , monocyte , immunology , lymphocyte , oncology , proportional hazards model , biomarker , breast cancer , gastroenterology , cancer , biology , biochemistry

Lymphocytes, neutrophils, and monocytes are vital effector cells in innate immunity. We postulated that lymphocyte to red blood cell ratio (LRR), neutrophil to red blood cell ratio (NRR), monocyte to red blood cell ratio (MRR) could represent the intensity of systemic inflammatory immunological reaction reflected through the lymphocyte, neutrophil and monocyte respectively. This study aimed to access the predictive and prognostic value of LRR, NRR, MRR and LRR-NRR-MRR score for locally advanced breast cancer.

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