Prognostic implications of the peripheral platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio in predicting pathologic complete response after neoadjuvant chemotherapy in breast cancer patients | Zendy

Xiaoyan Jin | Zendy; Ke Wang | Zendy; Xuan Shao | Zendy; Jian Huang | Zendy

Open Access

Prognostic implications of the peripheral platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio in predicting pathologic complete response after neoadjuvant chemotherapy in breast cancer patients

Author(s) -

Xiaoyan Jin,

Ke Wang,

Xuan Shao,

Jian Huang

Publication year - 2022

Publication title -

gland surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.643

H-Index - 22

eISSN - 2227-8575

pISSN - 2227-684X

DOI - 10.21037/gs-22-244

Subject(s) - medicine , anthracycline , breast cancer , oncology , odds ratio , confidence interval , receiver operating characteristic , neutrophil to lymphocyte ratio , neoadjuvant therapy , cutoff , logistic regression , taxane , lymphocyte , chemotherapy , cancer , gastroenterology , physics , quantum mechanics

The inflammatory response is extremely important in tumor progression, and it is very difficult to identify prognostic indicators for neoadjuvant therapy in breast cancer patients. The aim of this study was to mine the potential prognostic significance of the platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) in breast cancer patients receiving anthracycline- or taxane-based neoadjuvant chemotherapy (NACT).

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