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Mining the prognostic significance and immune infiltration of STAT family members in human breast cancer by bioinformatics analysis
Author(s) -
YuDong Zhou,
Siyuan Jiang,
Shibo Yu,
Lizhe Zhu,
Yang Liu,
Shouyu Li,
Na Hao,
Yu Ren
Publication year - 2022
Publication title -
gland surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.643
H-Index - 22
eISSN - 2227-8575
pISSN - 2227-684X
DOI - 10.21037/gs-22-189
Subject(s) - medicine , breast cancer , oncology , human protein atlas , hazard ratio , immune system , bioinformatics , gene , confidence interval , biology , cancer , immunology , genetics , protein expression
Growing evidence proved that signal transducer and activators of transcription ( STAT ) proteins are cytoplasmic transcription factors known to play key roles in many cellular biological processes and may be prognostic predictors of some cancers. However, the role of each STAT family members in breast cancer (BRCA) is diverse and controversial. This study aimed to systematic mine the prognostic significance and immune infiltration of STAT family member in human BRCA.

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