Identification of novel hub genes and lncRNAs related to the prognosis and progression of pancreatic cancer by microarray and integrated bioinformatics analysis | Zendy

Xing Liang | Zendy; Junfeng Peng | Zendy; Danlei Chen | Zendy; Liang Tang | Zendy; An-An Liu | Zendy; Zhiping Fu | Zendy; Ligang Shi | Zendy; Keqi Wang | Zendy; Chenghao Shao | Zendy

Open Access

Identification of novel hub genes and lncRNAs related to the prognosis and progression of pancreatic cancer by microarray and integrated bioinformatics analysis

Author(s) -

Xing Liang,

Junfeng Peng,

Danlei Chen,

Liang Tang,

An-An Liu,

Zhiping Fu,

Ligang Shi,

Keqi Wang,

Chenghao Shao

Publication year - 2021

Publication title -

gland surgery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.643

H-Index - 22

eISSN - 2227-8575

pISSN - 2227-684X

DOI - 10.21037/gs-21-151

Subject(s) - pancreatic cancer , gene , microarray , medicine , bioinformatics , microarray analysis techniques , cancer , identification (biology) , computational biology , gene expression , cancer research , biology , genetics , botany

Pancreatic cancer (PC) is one of the most invasive and metastatic neoplasms among the fatal malignancies of the digestive system. Abnormal expression of genes and long non-coding RNAs (lncRNAs) are reportedly linked to multiple cancers. However, the lncRNA-mRNA expression profiles and their molecular mechanisms in PC progression are poorly known. This study aimed to map the hub genes and lncRNAs which might play core roles in the development of PC.

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