Ginsenoside Rg3 protects heart against isoproterenol-induced myocardial infarction by activating AMPK mediated autophagy | Zendy

Guizhi Sun | Zendy; Fanji Meng | Zendy; Huaiqiu Cai | Zendy; Xue-Bo Diao | Zendy; Bo Zhang | Zendy; Bai Xiu-ping | Zendy

Open Access

Ginsenoside Rg3 protects heart against isoproterenol-induced myocardial infarction by activating AMPK mediated autophagy

Author(s) -

Guizhi Sun,

Fanji Meng,

Huaiqiu Cai,

Xue-Bo Diao,

Bo Zhang,

Bai Xiu-ping

Publication year - 2020

Publication title -

cardiovascular diagnosis and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.83

H-Index - 22

eISSN - 2223-3660

pISSN - 2223-3652

DOI - 10.21037/cdt.2020.01.02

Subject(s) - autophagy , ginseng , ampk , medicine , pharmacology , myocardial infarction , ginsenoside , cardioprotection , western blot , inflammasome , lactate dehydrogenase , protein kinase a , apoptosis , inflammation , kinase , enzyme , chemistry , biochemistry , pathology , alternative medicine , gene

Panax ginseng is a well-known medicinal herb that is widely used in traditional Chinese medicine for treating various diseases. Ginsenoside Rg3 (Rg3) is thought to be one of the most important active ingredients of Panax ginseng. However, the molecular mechanism underlying the beneficial effects of Rg3 has been elusive.

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