Impact of intracoronary reteplase during primary percutaneous coronary intervention on infarct size in large anterior myocardial infarction: rationale and design of the RECOVER II trial | Zendy

Dong Huang | Zendy; Yuanji Ma | Zendy; Hongxian Wu | Zendy; Xin Zhong | Zendy; Wei Gao | Zendy; Jun Zhou | Zendy; Juying Qian | Zendy; Junbo Ge | Zendy

Open Access

Impact of intracoronary reteplase during primary percutaneous coronary intervention on infarct size in large anterior myocardial infarction: rationale and design of the RECOVER II trial

Author(s) -

Dong Huang,

Yuanji Ma,

Hongxian Wu,

Xin Zhong,

Wei Gao,

Jun Zhou,

Juying Qian,

Junbo Ge

Publication year - 2022

Publication title -

cardiovascular diagnosis and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.83

H-Index - 22

eISSN - 2223-3660

pISSN - 2223-3652

DOI - 10.21037/cdt-21-756

Subject(s) - medicine , percutaneous coronary intervention , reteplase , myocardial infarction , cardiology , conventional pci , thrombus , perfusion , myocardial reperfusion , embolization , thrombolysis , surgery

Thrombus embolization and microvascular obstruction during percutaneous coronary intervention (PCI) in ST-segment elevation myocardial infarction (STEMI) is commonly detected, which causes inadequate myocardial perfusion and elevated infarct size. An approach with low-dose intracoronary fibrinolytic treatment for reducing distal embolization and improving myocardial reperfusion in high-risk STEMI cases remains controversial.

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