Left ventricular ischemia in pre-capillary pulmonary hypertension: a cardiovascular magnetic resonance study | Zendy

Karthigesh Sree Raman | Zendy; Ranjit Shah | Zendy; Michael B. Stokes | Zendy; Angela Walls | Zendy; Richard Woodman | Zendy; Rajiv Ananthakrishna | Zendy; Jennifer Walker | Zendy; Susanna Proudman | Zendy; Peter M. Steele | Zendy; Carmine G. De Pasquale | Zendy; David S. Celermajer | Zendy; Joseph B. Selvanayagam | Zendy

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Left ventricular ischemia in pre-capillary pulmonary hypertension: a cardiovascular magnetic resonance study

Author(s) -

Karthigesh Sree Raman,

Ranjit Shah,

Michael B. Stokes,

Angela Walls,

Richard Woodman,

Rajiv Ananthakrishna,

Jennifer Walker,

Susanna Proudman,

Peter M. Steele,

Carmine G. De Pasquale,

David S. Celermajer,

Joseph B. Selvanayagam

Publication year - 2020

Publication title -

cardiovascular diagnosis and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.83

H-Index - 22

eISSN - 2223-3660

pISSN - 2223-3652

DOI - 10.21037/cdt-20-698

Subject(s) - medicine , cardiology , coronary artery disease , magnetic resonance imaging , ischemia , pulmonary hypertension , pulmonary artery , endothelial dysfunction , radiology

Prognosis in pulmonary arterial hypertension (PAH) is largely dependent on right ventricular (RV) function. However, recent studies have suggested the presence of left ventricular (LV) dysfunction in PAH patients. The potential role of LV ischemia, as a contributor to progressive LV dysfunction, has not been systematically studied in PAH. We aim to assess the presence and extent of LV myocardial ischemia in patients with known PH and without obstructive coronary artery disease (CAD), using oxygen-sensitive (OS) cardiovascular magnetic resonance (CMR) and stress/rest CMR T1 mapping.

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