A longitudinal 18F-fluorodeoxyglucose (18F-FDG) and 18F-sodium fluoride (18F-NaF) positron emission tomography/computed tomography (PET/CT) study in apolipoprotein E (ApoE) knockout rats fed with a Western diet | Zendy

Xiaoqing Zhuang | Zendy; Yue Feng | Zendy; Juan Li | Zendy; Feng Zhao | Zendy; Yu Zhang | Zendy; Yue Chen | Zendy

Open Access

A longitudinal 18F-fluorodeoxyglucose (18F-FDG) and 18F-sodium fluoride (18F-NaF) positron emission tomography/computed tomography (PET/CT) study in apolipoprotein E (ApoE) knockout rats fed with a Western diet

Author(s) -

Xiaoqing Zhuang,

Yue Feng,

Juan Li,

Feng Zhao,

Yu Zhang,

Yue Chen

Publication year - 2021

Publication title -

cardiovascular diagnosis and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.83

H-Index - 22

eISSN - 2223-3660

pISSN - 2223-3652

DOI - 10.21037/cdt-20-609

Subject(s) - medicine , apolipoprotein e , positron emission tomography , standardized uptake value , calcification , magnetic resonance imaging , nuclear medicine , pathology , radiology , disease

Inflammation and vascular calcification are risk factors for cardiovascular disease, but their relationship is still under investigation. This longitudinal in vivo study aimed to monitor inflammation and calcification during the formation of atherosclerotic plaques in apolipoprotein E knockout (ApoE -/- ) rats by 18 F-fluorodeoxyglucose ( 18 F-FDG) and 18 F-sodium fluoride ( 18 F-NaF) positron emission tomography/computed tomography (PET/CT).

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