MicroRNA-363-3p serves as a diagnostic biomarker of acute myocardial infarction and regulates vascular endothelial injury by targeting KLF2 | Zendy

Chao Gao | Zendy; Hengbo Qian | Zendy; Qibiao Shi | Zendy; Hua Zhang | Zendy

Open Access

MicroRNA-363-3p serves as a diagnostic biomarker of acute myocardial infarction and regulates vascular endothelial injury by targeting KLF2

Author(s) -

Chao Gao,

Hengbo Qian,

Qibiao Shi,

Hua Zhang

Publication year - 2020

Publication title -

cardiovascular diagnosis and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.83

H-Index - 22

eISSN - 2223-3660

pISSN - 2223-3652

DOI - 10.21037/cdt-19-700

Subject(s) - medicine , myocardial infarction , biomarker , receiver operating characteristic , microrna , klf2 , coronary artery disease , umbilical vein , gene knockdown , cardiology , apoptosis , cancer research , downregulation and upregulation , biology , biochemistry , gene , in vitro

Acute myocardial infarction (AMI) is a serious cardiovascular disease. This study aimed to investigate the diagnostic value of microRNA-363-3p (miR-363-3p) in AMI patients and explore the effects of miR-363-3p on vascular endothelial injury in an AMI rat model.

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