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Division of Cellular Signaling, Institute for Advanced Medical Research, Division of General Thoracic Surgery, Department of Surgery, Keio University School of Medicine, Tokyo, Japan; Department of Immunology, School of Medicine, International University of Health and Welfare, Chiba, Japan Correspondence to: Yutaka Kawakami. Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjukuku, Tokyo 160-8582, Japan. Email: yutakawa@keio.jp; yutakawa@iuhw.ac.jp. Provenance: This is an invited article commissioned by the Editorial Office, Annals of Translational Medicine. Comment on: Masciale V, Grisendi G, Banchelli F, et al. Correlating tumor-infiltrating lymphocytes and lung cancer stem cells: a cross-sectional study. Ann Transl Med 2019;7:619.

Interface of cancer stem cells and cancer immunity