Open AccessActivating miRNA-mRNA network in gemcitabine-resistant pancreatic cancer cell associates with alteration of memory CD4+ T cells
Author(s) -
Jianyou Gu,
Junfeng Zhang,
Wenjie Huang,
Tian Tao,
Yaohuan Huang,
Ludi Yang,
Jiali Yang,
Yingfang Fan,
Huaizhi Wang
Publication year - 2020
Publication title -
annals of translational medicine
Language(s) - English
Resource type - Journals
eISSN - 2305-5847
pISSN - 2305-5839
DOI - 10.21037/atm.2020.03.53
Subject(s) - gemcitabine , microrna , pancreatic cancer , biology , immune system , cancer research , medicine , gene , oncology , cancer , immunology , genetics
Gemcitabine resistance can alter the fraction of memory CD4 T cells via hsa-miR-3178, hsa-miR-485-3p, hsa-miR-574-5p and hsa-miR-584-5p targeted MSI2, TEAD1, GNPDA1, RND3, PRKACB, TRIM68, and YKT6 network in PC.
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