Romosozumab, clinical trials, and real-world care of patients with osteoporosis

New Mexico Clinical Research & Osteoporosis Center, Albuquerque, NM, USA Correspondence to: E. Michael Lewiecki, MD. New Mexico Clinical Research & Osteoporosis Center, 300 Oak St. NE, Albuquerque, NM 87106, USA. Email mlewiecki@gmail.com. Provenance: This is an invited article commissioned by the Academic Editor Dr. Yusheng Li (Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, China). Comment on: McClung MR, Brown JP, Diez-Perez A, et al. Effects of 24 Months of Treatment With Romosozumab Followed by 12 Months of Denosumab or Placebo in Postmenopausal Women With Low Bone Mineral Density: A Randomized, Double-Blind, Phase 2, Parallel Group Study. J Bone Miner Res 2018;33:1397-406.