Open AccessMicroRNA-18a induces epithelial-mesenchymal transition like cancer stem cell phenotype via regulating RKIP pathway in pancreatic cancer
Author(s) -
Honggang Kang,
Dan Ma,
Jing Zhang,
Jun Zhao,
Mengxiang Yang
Publication year - 2020
Publication title -
annals of translational medicine
Language(s) - English
Resource type - Journals
eISSN - 2305-5847
pISSN - 2305-5839
DOI - 10.21037/atm.2020.03.195
Subject(s) - pancreatic cancer , epithelial–mesenchymal transition , cancer research , metastasis , microrna , cancer , cancer stem cell , phenotype , cancer cell , blot , biology , medicine , pathology , gene , biochemistry
We concluded that miR-181a induces EMT phenotype through its regulation of RKIP in pancreatic cancer. MicroRNA-18a may be a novel target in the treatment of pancreatic cancer in future.
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