Contribution of m6A subtype classification on heterogeneity of sepsis | Zendy

Shi Zhang | Zendy; Feng Liu | Zendy; Zongsheng Wu | Zendy; Jianfeng Xie | Zendy; Yi Yang | Zendy; Haibo Qiu | Zendy

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Contribution of m6A subtype classification on heterogeneity of sepsis

Author(s) -

Shi Zhang,

Feng Liu,

Zongsheng Wu,

Jianfeng Xie,

Yi Yang,

Haibo Qiu

Publication year - 2020

Publication title -

annals of translational medicine

Language(s) - English

Resource type - Journals

eISSN - 2305-5847

pISSN - 2305-5839

DOI - 10.21037/atm.2020.03.07

Subject(s) - sepsis , hazard ratio , mechanism (biology) , bioinformatics , gene , intensive care unit , computational biology , cluster (spacecraft) , cohort , biology , medicine , genetics , computer science , philosophy , epistemology , confidence interval , programming language

According to the heterogeneity in m6A methylation regulatory genes, three distinct subtypes in sepsis were identified with different RNA epigenetics, immune status, biological processes and outcomes, which initially uncovered that heterogeneity of sepsis may be largely caused by m6A RNA methylation.

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