Open AccessADAMTS12 acts as a cancer promoter in colorectal cancer via activating the Wnt/β-catenin signaling pathway in vitro
Author(s) -
Chunxue Li,
Xuelian Luo,
Bin Huang,
Xiangfeng Wang,
Yi Deng,
Zhaoyang Zhong
Publication year - 2020
Publication title -
annals of translational medicine
Language(s) - English
Resource type - Journals
eISSN - 2305-5847
pISSN - 2305-5839
DOI - 10.21037/atm.2020.02.154
Subject(s) - wnt signaling pathway , colorectal cancer , cancer research , cyclin d1 , signal transduction , biology , cell growth , cancer , cell cycle , microbiology and biotechnology , genetics
ADAMTS12 fulfills the tumor-promotor role by activating Wnt/β-catenin signaling pathway in colon cells and may represent a new option in CRC target treatment.
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