The immunoglobulin superfamily member 3 (IGSF3) promotes hepatocellular carcinoma progression through activation of the NF-κB pathway | Zendy

Ping Sheng | Zendy; Huirong Zhu | Zendy; Wenxiu Zhang | Zendy; Yanan Xu | Zendy; Wenxue Peng | Zendy; Jing Sun | Zendy; Mingqi Gu | Zendy; Hongchi Jiang | Zendy

Open Access

The immunoglobulin superfamily member 3 (IGSF3) promotes hepatocellular carcinoma progression through activation of the NF-κB pathway

Author(s) -

Ping Sheng,

Huirong Zhu,

Wenxiu Zhang,

Yanan Xu,

Wenxue Peng,

Jing Sun,

Mingqi Gu,

Hongchi Jiang

Publication year - 2020

Publication title -

annals of translational medicine

Language(s) - English

Resource type - Journals

eISSN - 2305-5847

pISSN - 2305-5839

DOI - 10.21037/atm.2020.02.14

Subject(s) - cancer research , cell growth , flow cytometry , blot , hepatocellular carcinoma , gene silencing , cell culture , biology , metastasis , in vivo , western blot , immunofluorescence , antibody , immunology , cancer , gene , biochemistry , genetics , microbiology and biotechnology

We found that IGSF3 can be used as a novel biomarker for HCC detection. Moreover, IGSF3 elicits HCC progression by activating the NF-κB pathway. As such, our data provides potential options for therapeutic targets in patients with HCC.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research