Open AccessMorusin exerts anti-cancer activity in renal cell carcinoma by disturbing MAPK signaling pathways
Author(s) -
Chengfei Yang,
Jing Luo,
Xing Luo,
Weisheng Jia,
Zhenqiang Fang,
Shanhong Yi,
Longkun Li
Publication year - 2020
Publication title -
annals of translational medicine
Language(s) - English
Resource type - Journals
eISSN - 2305-5847
pISSN - 2305-5839
DOI - 10.21037/atm.2020.02.107
Subject(s) - cell cycle , cell growth , apoptosis , cancer research , mapk/erk pathway , carcinogenesis , g1 phase , cell cycle checkpoint , biology , cell , flow cytometry , nude mouse , cancer , signal transduction , microbiology and biotechnology , biochemistry , genetics
Our results show that morusin could inhibit the growth of RCC cells and through MAPK signal pathways. Thus, morusin could be a potential anti-cancer agent for RCC.
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