Mesenchymal stromal cells ameliorate acute lung injury induced by LPS mainly through stanniocalcin-2 mediating macrophage polarization | Zendy

Haijin Lv | Zendy; Qiuli Liu | Zendy; Yao Sun | Zendy; Xiaomeng Yi | Zendy; Xuxia Wei | Zendy; Wei Liu | Zendy; Qi Zhang | Zendy; Huimin Yi | Zendy; Guihua Chen | Zendy

Open Access

Mesenchymal stromal cells ameliorate acute lung injury induced by LPS mainly through stanniocalcin-2 mediating macrophage polarization

Author(s) -

Haijin Lv,

Qiuli Liu,

Yao Sun,

Xiaomeng Yi,

Xuxia Wei,

Wei Liu,

Qi Zhang,

Huimin Yi,

Guihua Chen

Publication year - 2020

Publication title -

annals of translational medicine

Language(s) - Uncategorized

Resource type - Journals

eISSN - 2305-5847

pISSN - 2305-5839

DOI - 10.21037/atm.2020.02.105

Subject(s) - mesenchymal stem cell , flow cytometry , gene knockdown , macrophage polarization , cancer research , paracrine signalling , apoptosis , stromal cell , inflammation , macrophage , microbiology and biotechnology , immunology , biology , medicine , in vitro , biochemistry , receptor

Collectively, these results suggested that STC2 is essential to the anti-oxidative and anti-inflammation properties of MSCs and could prove to be crucial for stem cell therapies for ALI.

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