Efficacy of switching therapy to aflibercept for patients with persistent diabetic macular edema: a systematic review and meta-analysis | Zendy

Yilin Liu | Zendy; Jiahan Cheng | Zendy; Yunxia Gao | Zendy; Ling Qin | Zendy; Xiaoxue Min | Zendy; Ming Zhang | Zendy

Open Access

Efficacy of switching therapy to aflibercept for patients with persistent diabetic macular edema: a systematic review and meta-analysis

Author(s) -

Yilin Liu,

Jiahan Cheng,

Yunxia Gao,

Ling Qin,

Xiaoxue Min,

Ming Zhang

Publication year - 2020

Publication title -

annals of translational medicine

Language(s) - English

Resource type - Journals

eISSN - 2305-5847

pISSN - 2305-5839

DOI - 10.21037/atm.2020.02.04

Subject(s) - aflibercept , medicine , ranibizumab , bevacizumab , ophthalmology , visual acuity , cochrane library , adverse effect , diabetic macular edema , meta analysis , macular edema , subgroup analysis , diabetic retinopathy , diabetes mellitus , chemotherapy , endocrinology

This meta-analysis indicated the comparable efficacy and safety of a conversion treatment to aflibercept in cases of unsatisfactory responses to other anti-VEGF drugs. Switching treatment produces significant advantage for vision acuity recovery and macular edema improvement among persistent DME patients.

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