When data interpretation should not rely on the magnitude of P values: the example of ANDROMEDA SHOCK trial

Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy; Department of Anesthesia and Intensive Care, Ente Ospedaliero Ospedali Galliera, Italy; Department of Clinical Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy; Anaesthesia, Intensive Care and Pain Therapy, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy Correspondence to: Prof. Francesco Corradi. Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, Via Paradisa 2, 56124, University of Pisa, Pisa, Italy. Email: francescorradi@gmail.com. Comment on: Zampieri FG, Damiani LP, Bakker J, et al. Effects of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels Among Patients with Septic Shock: A Bayesian Reanalysis of the ANDROMEDA-SHOCK Trial. Am J Respir Crit Care Med 2020;201:423-9.