Yin Zhi Huang, a traditional Chinese herbal formula, ameliorates diet-induced obesity and hepatic steatosis by activating the AMPK/SREBP-1 and the AMPK/ACC/CPT1A pathways | Zendy

Qunyan Yao | Zendy; Shuyu Li | Zendy; Xinlai Cheng | Zendy; Yanting Zou | Zendy; Yue Shen | Zendy; Shuncai Zhang | Zendy

Open Access

Yin Zhi Huang, a traditional Chinese herbal formula, ameliorates diet-induced obesity and hepatic steatosis by activating the AMPK/SREBP-1 and the AMPK/ACC/CPT1A pathways

Author(s) -

Qunyan Yao,

Shuyu Li,

Xinlai Cheng,

Yanting Zou,

Yue Shen,

Shuncai Zhang

Publication year - 2020

Publication title -

annals of translational medicine

Language(s) - English

Resource type - Journals

eISSN - 2305-5847

pISSN - 2305-5839

DOI - 10.21037/atm.2020.01.31

Subject(s) - lipogenesis , ampk , steatosis , medicine , endocrinology , oil red o , fatty liver , fatty acid synthase , beta oxidation , adipose tissue , chemistry , biology , lipid metabolism , biochemistry , adipogenesis , protein kinase a , metabolism , kinase , disease

YZH supplementation ameliorated diet-induced obesity and hepatic steatosis by decreasing AMPK/SREBP-1 pathway-mediated lipogenesis and increasing AMPK/ACC/CPT1A pathway-mediated mitochondrial fatty acid β oxidation.

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