The E3 ligase malin plays a pivotal role in promoting nuclear glycogenolysis and histone acetylation

Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, USA; Markey Cancer Center University of Kentucky, Lexington, KY, USA; Department of Neuroscience, University of Kentucky, Lexington, KY, USA Correspondence to: Matthew S. Gentry; Ramon C. Sun. University of Kentucky, 741 South Limestone Street, B179, Lexington, KY 40536-0509, USA. Email: matthew.gentry@uky.edu; ramon.sun@uky.edu. Provenance and Peer Review: This article was commissioned and reviewed by the Section Editor Dr. Ran Mo (Department of Burn and Plastic Surgery, Nanjing Drum Tower Hospital, Nanjing, China). Response to: Feron O. The many metabolic sources of acetyl-CoA to support histone acetylation and influence cancer progression. Ann Transl Med 2019;7:S277.