Teasaponin suppresses Candida albicans filamentation by reducing the level of intracellular cAMP | Zendy

Ying Li | Zendy; Mingzhu Shan | Zendy; Shihui Li | Zendy; Yuechen Wang | Zendy; Huan Yang | Zendy; Ying Chen | Zendy; Bing Gu | Zendy; Zuobin Zhu | Zendy

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Teasaponin suppresses Candida albicans filamentation by reducing the level of intracellular cAMP

Author(s) -

Ying Li,

Mingzhu Shan,

Shihui Li,

Yuechen Wang,

Huan Yang,

Ying Chen,

Bing Gu,

Zuobin Zhu

Publication year - 2020

Publication title -

annals of translational medicine

Language(s) - English

Resource type - Journals

eISSN - 2305-5847

pISSN - 2305-5839

DOI - 10.21037/atm.2020.01.124

Subject(s) - filamentation , candida albicans , biofilm , corpus albicans , microbiology and biotechnology , in vivo , intracellular , cytotoxicity , in vitro , biology , yeast , chemistry , bacteria , biochemistry , genetics , laser , physics , optics

Our work evaluated the antifungal activity of TS against filamentation and biofilms formation of and disclosed the underlying mechanism, which might provide useful clues for the potential clinical application of TS in fighting clinical fungal infections by targeting the virulence factors.

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