Tumor slice culture as a biologic surrogate of human cancer | Zendy

Heidi L. Kenerson | Zendy; Kevin M. Sullivan | Zendy; Yongwoo David Seo | Zendy; Kathryn M. Stadeli | Zendy; Cigdem Ussakli | Zendy; Xiaowei Yan | Zendy; Chris Lausted | Zendy; Venu G. Pillarisetty | Zendy; James O. Park | Zendy; Kimberly J. Riehle | Zendy; Matthew M. Yeh | Zendy; Qiang Tian | Zendy; Raymond S. Yeung | Zendy

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Tumor slice culture as a biologic surrogate of human cancer

Author(s) -

Heidi L. Kenerson,

Kevin M. Sullivan,

Yongwoo David Seo,

Kathryn M. Stadeli,

Cigdem Ussakli,

Xiaowei Yan,

Chris Lausted,

Venu G. Pillarisetty,

James O. Park,

Kimberly J. Riehle,

Matthew M. Yeh,

Qiang Tian,

Raymond S. Yeung

Publication year - 2020

Publication title -

annals of translational medicine

Language(s) - English

Resource type - Journals

eISSN - 2305-5847

pISSN - 2305-5839

DOI - 10.21037/atm.2019.12.88

Subject(s) - tumor microenvironment , ex vivo , cancer , in vivo , pathology , vibratome , medicine , colorectal cancer , cancer research , biology , immunohistochemistry , microbiology and biotechnology

We report a standardized method to assess and compare human cancer growth ex vivo across a wide spectrum of tumor samples. TSC reflects the state of tumor behavior and heterogeneity, thus providing a simple approach to study of human cancers with an intact TME.

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