The protective effect of Lonicera japonica polysaccharide on mice with depression by inhibiting NLRP3 inflammasome | Zendy

Ping Liu | Zendy; Xinyu Bai | Zendy; Tao Zhang | Zendy; Limei Zhou | Zendy; Jing Li | Zendy; Lan Zhang | Zendy

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The protective effect of Lonicera japonica polysaccharide on mice with depression by inhibiting NLRP3 inflammasome

Author(s) -

Ping Liu,

Xinyu Bai,

Tao Zhang,

Limei Zhou,

Jing Li,

Lan Zhang

Publication year - 2019

Publication title -

annals of translational medicine

Language(s) - English

Resource type - Journals

eISSN - 2305-5847

pISSN - 2305-5839

DOI - 10.21037/atm.2019.12.64

Subject(s) - open field , inflammasome , tail suspension test , stimulation , japonica , hippocampus , polysaccharide , behavioural despair test , depression (economics) , elevated plus maze , pharmacology , chemistry , medicine , endocrinology , biology , biochemistry , psychiatry , inflammation , anxiety , botany , macroeconomics , economics , antidepressant

LJP exhibited a strong protective effect on mice with depression by inhibiting NLRP3 inflammasome. The results will help to understand the potential use of Lonicera japonica Thun polysaccharide in pharmaceutical and food applications better.

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