Glycosylation alterations in acute pancreatitis and pancreatic cancer: CA19-9 expression is involved in pathogenesis and maybe targeted by therapy | Zendy

Ionuţ Negoi | Zendy; Mircea Beuran | Zendy; Sorin Hostiuc | Zendy; Massimo Sartelli | Zendy; Alaa ElHussuna | Zendy; Enrique deMadaria | Zendy

Open Access

Glycosylation alterations in acute pancreatitis and pancreatic cancer: CA19-9 expression is involved in pathogenesis and maybe targeted by therapy

Author(s) -

Ionuţ Negoi,

Mircea Beuran,

Sorin Hostiuc,

Massimo Sartelli,

Alaa ElHussuna,

Enrique deMadaria

Publication year - 2019

Publication title -

annals of translational medicine

Language(s) - English

Resource type - Journals

eISSN - 2305-5847

pISSN - 2305-5839

DOI - 10.21037/atm.2019.10.72

Subject(s) - pathogenesis , pancreatic cancer , pancreatitis , ca19 9 , medicine , glycosylation , cancer research , acute pancreatitis , cancer , bioinformatics , biology , biochemistry

Dear editor, we have read with great interest the basic research paper entitled ‘ The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice ’, published recently by Engle et al . in the Science journal (1). This paper underline that CA 19-9 is not only the most used and well-known tumor biomarker for pancreatic cancer (2), but an active player in the acute pancreatitis and pancreatic cancer pathogenesis, and a potential target for future therapies (1).

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research