Differential expression of genes associated with hypoxia pathway on bone marrow stem cells in osteoporosis patients with different bone mass index | Zendy

Qi Zhu | Zendy; Shan Chang | Zendy; Ling Li | Zendy; Lige Song | Zendy; KeQin Zhang | Zendy; Yun Zhou | Zendy

Open Access

Differential expression of genes associated with hypoxia pathway on bone marrow stem cells in osteoporosis patients with different bone mass index

Author(s) -

Qi Zhu,

Shan Chang,

Ling Li,

Lige Song,

KeQin Zhang,

Yun Zhou

Publication year - 2019

Publication title -

annals of translational medicine

Language(s) - English

Resource type - Journals

eISSN - 2305-5847

pISSN - 2305-5839

DOI - 10.21037/atm.2019.06.27

Subject(s) - bone marrow , hypoxia (environmental) , osteoporosis , bone marrow stem cell , medicine , body mass index , endocrinology , stem cell , gene , bone remodeling , biology , microbiology and biotechnology , genetics , chemistry , organic chemistry , oxygen

The expression of genes associated with hypoxia pathway on BMSCs in OP patients are lower than healthy subjects, and the expression of genes related to carbohydrate metabolism are lower in overweight OP patients than in normal weight OP patients. These results need further research.

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