Effects of atypical antipsychotic drugs on QT interval in patients with mental disorders
Author(s) -
Wilbert S. Aronow,
Tatyana Shamliyan
Publication year - 2018
Publication title -
annals of translational medicine
Language(s) - English
Resource type - Journals
eISSN - 2305-5847
pISSN - 2305-5839
DOI - 10.21037/atm.2018.03.17
Subject(s) - ziprasidone , quetiapine , olanzapine , medicine , qt interval , aripiprazole , torsades de pointes , risperidone , antipsychotic , randomized controlled trial , atypical antipsychotic , psychiatry , schizophrenia (object oriented programming)
The main conclusion of our study is that in people with mental disorders and under treatment with atypical antipsychotic drugs, in order to avoid QT prolongation and reduce the risk of ventricular tachycardia clinicians may recommend aripiprazole, brexpiprazole or olanzapine in licensed doses. Long-term comparative safety needs to be established.
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