Open AccessAB098. Genotype-phenotype association studies in patients with Beta-thalassemia: a systematic review
Author(s) -
April Grace Berboso,
Catherine Lynn T. Silao,
Leonila F. Dans
Publication year - 2017
Publication title -
annals of translational medicine
Language(s) - English
Resource type - Journals
eISSN - 2305-5847
pISSN - 2305-5839
DOI - 10.21037/atm.2017.s098
Subject(s) - beta thalassemia , phenotype , thalassemia , genotype , medicine , beta (programming language) , genetics , bioinformatics , biology , gene , computer science , programming language
Background It is known that type of β-globin (HBB) gene mutation primarily affects the severity of beta-thalassemia disease. This study aimed to determine the association of different types of HBB mutation and genetic modifiers with disease manifestations (phenotypes) in β-thalassemia.
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