Andrographolide alleviates bleomycin-induced NLRP3 inflammasome activation and epithelial-mesenchymal transition in lung epithelial cells by suppressing AKT/mTOR signaling pathway
Author(s) -
Jingpei Li,
Xiaohan Yang,
Penghui Yang,
Ke Xu,
Xiaomin Peng,
Weipeng Cai,
Simin Zhao,
Lei Hu,
Zhuoyi Li,
Fei Cui,
Wei Wang,
Guilin Peng,
Xin Xu,
Jianxing He,
Jun Liu
Publication year - 2021
Publication title -
annals of translational medicine
Language(s) - English
Resource type - Journals
eISSN - 2305-5847
pISSN - 2305-5839
DOI - 10.21037/atm-20-7973
Subject(s) - inflammasome , andrographolide , pi3k/akt/mtor pathway , protein kinase b , a549 cell , chemistry , cancer research , bleomycin , epithelial–mesenchymal transition , pulmonary fibrosis , signal transduction , microbiology and biotechnology , pharmacology , fibrosis , apoptosis , medicine , biology , receptor , downregulation and upregulation , biochemistry , chemotherapy , gene
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