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Department of Clinical Medicine and Surgery, Gastroenterology Unit, University of Napoli Federico II, Napoli, Italy Correspondence to: Filomena Morisco. Department of Clinical Medicine and Surgery, Gastroenterology Unit, University of Naples Federico II, Napoli, Italy. Email: filomena.morisco@unina.it. Comment on: Zhao S, Zhang X, Wang M, et al. Identifying optimal candidates for liver resection or transarterial chemoembolisation in patients with unresectable hepatocellular carcinoma. Ann Transl Med 2020;8:586.

annals of translational medicine

Liver resection is always a good choice for hepatocellular carcinoma (HCC) patients regardless of Barcelona Clinic Liver Cancer (BCLC) stage: the therapeutic hierarchy