Lymphotoxin beta receptor is associated with regulation of microRNAs expression and nuclear factor-kappa B activation in lipopolysaccharides (LPS)-stimulated vascular smooth muscle cells
Author(s) -
Ling Xiao,
Wen Mei,
Zezhou Xiao,
Zhiwen Luo,
Jiawei Zhuang,
Qianqin Li,
Songlin Du,
Shaoyi Zheng,
Peng Zhu
Publication year - 2020
Publication title -
annals of palliative medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.546
H-Index - 19
eISSN - 2224-5839
pISSN - 2224-5820
DOI - 10.21037/apm.2020.03.20
Subject(s) - medicine , lymphotoxin , microrna , inflammation , receptor , vascular smooth muscle , lymphotoxin alpha , nfkb1 , lymphotoxin beta receptor , microbiology and biotechnology , lipopolysaccharide , nf κb , cancer research , immunology , smooth muscle , gene , transcription factor , biology , biochemistry
The aim of present study is to investigate the role of lymphotoxin beta receptor (Ltβr) in lipopolysaccharides (LPS)-induced inflammation in vascular smooth muscle cells (VSMCs) and whether its effects are mediated by modulating microRNAs (miRNAs) and nuclear factor-kappa B (NF-κB).
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom