Development and in vitro characterization of rifapentine microsphere-loaded bone implants: a sustained drug delivery system | Zendy

Zhen Wang | Zendy; Xinghua Song | Zendy; Huan Yang | Zendy; Abulikemu Maimaitiaili | Zendy; Tengfei Wang | Zendy

Open Access

Development and in vitro characterization of rifapentine microsphere-loaded bone implants: a sustained drug delivery system

Author(s) -

Zhen Wang,

Xinghua Song,

Huan Yang,

Abulikemu Maimaitiaili,

Tengfei Wang

Publication year - 2020

Publication title -

annals of palliative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 19

eISSN - 2224-5839

pISSN - 2224-5820

DOI - 10.21037/apm.2020.03.13

Subject(s) - drug delivery , rifapentine , medicine , alkaline phosphatase , in vitro , pharmacology , drug , biomedical engineering , chemistry , pathology , materials science , biochemistry , nanotechnology , mycobacterium tuberculosis , tuberculosis , latent tuberculosis , enzyme

This study aimed to develop and evaluate a sustained drug delivery system for the treatment of osteoarticular tuberculosis (TB) to address the issues surrounding low drug concentration in lesions and bone defects or nonunion after debridement.

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