Impact of blood-brain barrier disruption on newly diagnosed neuromyelitis optica spectrum disorder symptoms and prognosis | Zendy

Shuolin Liang | Zendy; Qiuhong Qin | Zendy; Yulan Tang | Zendy; Weijing Liao | Zendy; Yi Yang | Zendy; Jinrong He | Zendy; Liangsheng Li | Zendy

Open Access

Impact of blood-brain barrier disruption on newly diagnosed neuromyelitis optica spectrum disorder symptoms and prognosis

Author(s) -

Shuolin Liang,

Qiuhong Qin,

Yulan Tang,

Weijing Liao,

Yi Yang,

Jinrong He,

Liangsheng Li

Publication year - 2020

Publication title -

annals of palliative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 19

eISSN - 2224-5839

pISSN - 2224-5820

DOI - 10.21037/apm.2019.12.12

Subject(s) - medicine , neuromyelitis optica , spectrum disorder , pediatrics , intensive care medicine , psychiatry , multiple sclerosis

Blood-brain barrier (BBB) disruption and ensuing immune activation are central to the pathogenesis of central nervous system (CNS) inflammatory diseases. However, the influence of BBB permeability on the clinical signs and prognosis of newly diagnosed neuromyelitis optica spectrum disorder (NMOSD) has not been examined. We investigate the relationships between BBB permeability as showed by the albumin quotient (qalb) and clinical features of NMOSD.

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