Genetic biomarkers associated with pain flare and dexamethasone response following palliative radiotherapy in patients with painful bone metastases | Zendy

Anthony Furfari | Zendy; Bo Wan | Zendy; Keyue Ding | Zendy; Andrew Wong | Zendy; Liting Zhu | Zendy; Andrea Bezjak | Zendy; Rebecca Wong | Zendy; Carolyn F. Wilson | Zendy; Carlo DeAngelis | Zendy; Azar Azad | Zendy; Edward Chow | Zendy; George S. Charames | Zendy

Open Access

Genetic biomarkers associated with pain flare and dexamethasone response following palliative radiotherapy in patients with painful bone metastases

Author(s) -

Anthony Furfari,

Bo Wan,

Keyue Ding,

Andrew Wong,

Liting Zhu,

Andrea Bezjak,

Rebecca Wong,

Carolyn F. Wilson,

Carlo DeAngelis,

Azar Azad,

Edward Chow,

George S. Charames

Publication year - 2017

Publication title -

annals of palliative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 19

eISSN - 2224-5839

pISSN - 2224-5820

DOI - 10.21037/apm.2017.09.04

Subject(s) - medicine , dexamethasone , flare , incidence (geometry) , confidence interval , bone pain , glucocorticoid , physics , astrophysics , optics

In patients who receive palliative radiation therapy (RT) for painful bone metastases, 40% experience a transient increase in pain known as a pain flare. Prophylactic dexamethasone has been shown to reduce pain flare incidence to 25%. We aimed to identify DNA biomarkers associated with pain flare and dexamethasone response.

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