In vitro bacteriostatic effects of Polymyxin B combined with Propofol medium and long chain fat emulsion injection against Escherichia coli | Zendy

Lei Qi | Zendy; Yue Wang | Zendy; Bairong Chen | Zendy; Yuting Ren | Zendy; Guomin Mao | Zendy; Guiwen Liang | Zendy; Wei Liu | Zendy; Yang Zhou | Zendy; Zhongwei Huang | Zendy; Kai Sun | Zendy; Haiyan Jiang | Zendy

Open Access

In vitro bacteriostatic effects of Polymyxin B combined with Propofol medium and long chain fat emulsion injection against Escherichia coli

Author(s) -

Lei Qi,

Yue Wang,

Bairong Chen,

Yuting Ren,

Guomin Mao,

Guiwen Liang,

Wei Liu,

Yang Zhou,

Zhongwei Huang,

Kai Sun,

Haiyan Jiang

Publication year - 2021

Publication title -

annals of palliative medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.546

H-Index - 19

eISSN - 2224-5839

pISSN - 2224-5820

DOI - 10.21037/apm-21-751

Subject(s) - medicine , escherichia coli , emulsion , polymyxin , polymyxin b , microbiology and biotechnology , in vitro , propofol , fat emulsion , pharmacology , antibiotics , biochemistry , intensive care medicine , parenteral nutrition , biology , gene

Polymyxins is a class of cyclic polypeptide antibiotics with strong antibacterial activity against Gram-negative bacteria. However, bacteria become resistant to Polymyxins. Thus, Polymyxin B (PMB) in combination with other antimicrobials may be a better choice in clinic. This study aimed to evaluate the synergistic bacteriostatic effect of PMB combined with Propofol medium and long chain fat emulsion injection against Escherichia coli in vitro.

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