Tiaochang Xiaoliu Decoction Granules prevent the recurrence of colorectal adenoma: a study protocol for a randomized controlled trial
Author(s) -
Cailing Zhong,
ShaoHua Wu,
Chunhui Chen,
Haocheng Huang,
Jiahao Mo,
Xiaobo Yang,
Chen Yan,
Beiping Zhang
Publication year - 2021
Publication title -
annals of palliative medicine
Language(s) - English
Resource type - Journals
eISSN - 2224-5839
pISSN - 2224-5820
DOI - 10.21037/apm-21-650
Subject(s) - medicine , colonoscopy , polypectomy , decoction , adenoma , colorectal cancer , randomized controlled trial , colorectal adenoma , incidence (geometry) , clinical trial , gastroenterology , cancer , physics , optics
With the changes in lifestyle and diet, the incidence and mortality of colorectal cancer (CRC) is increasing in China. CRC mainly develops from colorectal adenomas (CRAs). There is a lack of chemopreventative drugs with definite efficacy for CRAs. Tiaochang Xiaoliu Decoction (TXD) was developed by Professor Yunjian Luo and has been used clinically over the last ten years for the prevention of CRA recurrence. To facilitate its clinical use, TXD was further standardized and produced as "Tiaochang Xiaoliu Decoction Granules (TXDG)". A study was designed to investigate the preventive effects of TXDG on the recurrence of CRA.
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