microRNA-181a promotes the proliferation of hypertrophic scar fibroblasts and inhibits their apoptosis via targeting phosphatase and tensin homolog | Zendy

Yanpeng Zhou | Zendy; Xun Shi | Zendy; Shengfei Li | Zendy; Quan Gan | Zendy; Zhengjun Cui | Zendy

Open Access

microRNA-181a promotes the proliferation of hypertrophic scar fibroblasts and inhibits their apoptosis via targeting phosphatase and tensin homolog

Author(s) -

Yanpeng Zhou,

Xun Shi,

Shengfei Li,

Quan Gan,

Zhengjun Cui

Publication year - 2021

Publication title -

annals of palliative medicine

Language(s) - English

Resource type - Journals

eISSN - 2224-5839

pISSN - 2224-5820

DOI - 10.21037/apm-21-604

Subject(s) - pten , tensin , apoptosis , transfection , cell growth , phosphatase , western blot , microbiology and biotechnology , microrna , hypertrophic scar , cancer research , lipofectamine , medicine , biology , cell culture , pathology , pi3k/akt/mtor pathway , phosphorylation , gene , biochemistry , genetics , recombinant dna , vector (molecular biology)

This study aimed to compare the expression of microRNA (miR)-181a and phosphatase and tensin homolog (PTEN) in hypertrophic scar tissue and cells and to explore the effects of miR-181a and PTEN on the proliferation and apoptosis of the human scar fibroblast cell line HSFb.

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